Immunology/Immunohematology Syllabus for 2017-2018
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Instructor Information

Office Location

<p>West Campus Allied Health 151A</p>

Office Hours

by appointment

Course Information

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Course

MLAB-2573-001 Immunology/Immunohematology

Prerequisites

<p>Corequisite: MLAB 1211</p>

Course Description

An introduction to the theory and application of basic immunology, including the immune response, principles of antigen-antibody reactions, and the principles of serological procedures as well as quality control, quality assurance and safety. In addition, a study of blood antigens and antibodies. Includes the principles, procedures and clinical significance of test results in genetics, blood group systems, pre-transfusion testing, adverse effects of transfusions, donor selection and components, and hemolytic disease of the newborn.

Student ResourcesStudent Resources Website

Department Expectations

Occupational License Disclaimer

Notice to Students enrolled in an educational program for preparation of issuance of certain occupational licenses:

Students enrolled in an educational program in preparation for obtaining certain occupational licenses are potentially ineligible for such license if the student has been convicted of an offense. For further information, please contact your advisor, the Legal Clinic, or the faculty member in charge of the educational program that you seek to enroll in. The further information you will receive will include notification to you of your right to request a criminal history evaluation letter from the licensing authority in order to clarify your particular situation.

Hours

(5 sem hrs; 3 lec, 8 lab)

Class Type

On Campus Course

Syllabus Information

Textbooks

Clincial Immunology and Serology, A Laboratory Perspective, 4th Ed., Stevens, FA Davis, 2017, ISBN:978-0-8036-4466-3
Basic and Applied Concepts of Blood Banking and Transfusion Practices, 4th Ed, Howard, Mosby, 201

Supplies

The supplies include the following:

  • Textbook(s) and lab manual
  • Computer or Tablet with Respondus Lockdown browser installed
  • Internet access
  • Disposable lab coat
  • Gloves (preferably nitrile) not vinyl
  • Sharpies
  • Pens/pencils/paper

Student Performance

COURSE OUTCOMES

Apply principles of safety, quality assurance and quality control in Immunohematology; evaluate specimen acceptability; describe blood group genetics, characteristics of the blood group systems, and the principles of immunology as they relate to immunohematology; list the requirements for the donation of blood; and describe the preparation, storage, and use of blood components; evaluate laboratory test results; select additional procedures to be performed; correlate test results with patient conditions; and describe the principles of and perform routine blood bank tests.

Specific learning objectives for each section and each laboratory exercise are distributed as part of the lecture/lab handouts.

Students Rights and Responsibilities

Student Rights and Responsibilities

Log in using the AC Connect Portal

In order to receive your AC Connect Email, you must log in through AC Connect at https://acconnect.actx.edu .

If you are an active staff or faculty member according to Human Resources, use "Exchange". All other students, use "AC Connect (Google) Email".

Expected Student Behavior

ACADEMIC DISHONESTY
Academic dishonesty shall constitute a violation of the college rules and regulations and is punishable as prescribed by Amarillo College Board policies. Academic dishonesty shall include, but is not limited to, cheating on a test/quiz/assignment, plagiarism, and collusion. Cheating shall include:
  • Copying from another student's test/assignment paper.
  • Using test materials not authorized by the person administering the test/assignment (ex: notes, books, etc).
  • Collaborating with or seeking aid from another student during a test/assignment without permission from the test/assignment administrator/instructor.
  • Knowingly using, buying, selling, stealing, or soliciting, in whole or in part, the contents of an administered/unadministered test/assignment.
  • The unauthorized transporting or removal, in whole or in part, of the contents of the administered/unadministered test/assignment.
  • Substituting for another student, or permitting another student to substitute for one's self, to take a test/assignment.
  • Bribing another person to obtain an administered/unadministered test/assignment or information about an administered/unadministered test/assignment.
Plagiarism shall be defined as the appropriating, buying, receiving as a gift, or obtaining by any means another's work and the unacknowledged submission or incorporation of it in one's own written work.
Collusion shall be defined as the unauthorized collaboration with another person in preparing written work for fulfillment of course requirements.
WORK ETHICS
Amarillo College and the Medical Laboratory Technology program are committed to developing knowledge, skills, attitudes, and behaviors in students so that they can obtain entry-level employment and advance in their chosen profession. Great measures are taken to ensure that the curriculum is updated and that equipment is purchased and kept at industry level, as much as possible. Program Advisory committees meet annually to ensure that the curriculum meets the needs of the local medical community as well as the program's national accrediting agency.
We are committed to providing these things to ensure that a graduate has the skills and knowledge to obtain and advance in their chosen profession. Therefore, professional education must address more than academic and skills training in order to meet this challenge. Business and industry state that their greatest need is for employees who possess strong work ethics. Therefore, we accept the challenge of providing not only academic and hands-on training but also work ethics training to students. The work ethics program is important because it provides the link between academic knowledge, skills training and successful employment in the workforce. The program focuses on those behaviors expected in a professional environment.
The following work ethics have been identified as being most important to professional employers, and will be covered and evaluated on a weekly basis, each semester, throughout the program:
  • Attendance
  • Character
  • Teamwork
  • Appearance
  • Attitude
  • Productivity
  • Organization
  • Communication
  • Cooperation
  • Respect
NOTE: If a student is absent during a scheduled lecture/lab period, he/she cannot be awarded points for work ethics during that missed lecture/lab period.
CELL PHONES
Cell phones are disruptive during lecture and lab sessions. Cell phones should be turned-off during class time, or set on vibrate or "silent" during class time. If the student anticipates an emergency during class time, they should leave the number for the Student Services Office with their contact. The number is 371-5300.
 
Text/Instant Messaging is NOT permitted when lectures and labs are in session.  It is disruptive and disrespectful to fellow students and the course instructor. Students who are caught engaging in either of these will be subject to disciplinary action including, but not limited to:
  1. Being asked to leave class for the remainder of the day
  2. Mandatory conference with the Assistant Dean of Career and Technical Programs
  3. Conference with the Dean of Students and a permanent entry in the student's official program record

    The ONLY exception that will be made is if the student has discussed the situation with their instructor beforehand, and ONLY for emergency purposes.
GRIEVANCE PROCEDURE  If a student is having a problem with the course policies or the instructor, he or she should first try and resolve any such problems through the instructor. If the problem is not resolved, the student may proceed to the Program Director, the Dean of Health Sciences (Mark Rowh), Vice President of of Academic Affairs (Dr Tamra Clunis), and the College President (Dr Russel Lowery-Hart), IN THAT ORDER.

 

Grading Criteria

The course components of this course will be weighted as follows:
Lecture = 65% of the total grade
Lab = 10% of the total grade
Work Ethics = 5% of the total grade
 Final Exams = 20% of the total grade
The grading scale used for this course is as follows:
A = 90.0% - 100.0% of the total points possible for the course 
B = 80.0% - 89.9% of the total points possible for the course
C = 70.0% - 79.9% of the total points possible for the course
F = 69.9% or less of the total points possible for the course
NOTE: A grade of 'D' is not possible
 
Examinations and quizzes may not be made up. Students will be given each unit exam and final exam in class.
 
Students are not allowed to make up the labs. The study questions for each lab are due the day the lab is performed, if that lab is missed the study questions will only be worth half the original points.
 
Major examinations will be given over the lecture and reading material. A comprehensive final will be given at the end of this course. Quizzes may be given, announced or unannounced, at any time, so the student is advised to complete all assignments in a timely manner in order to be successful on quizzes. No credit will be given for assignments, notebooks, etc..., turned in after the specified date. A total accumulative point system is used to calculate the final grade average and is comprised of the following:
1.  Notebooks/or class files are worth a possible total of 25 points.
2.  Major Lecture Examinations (100 points possible per exam)
3.  Lab procedures and study questions (10-25 points, possible)
4.  Quizzes (5-25 points possible, each)
5.  Work Ethics: (0 - 10 possible per class day, based on work ethic discussions, assignments, and student demonstration of positive work ethic qualities, as evaluated by their instructor(s)
 
There are four final exams:
1.  A Lecture exam in Immunology, a lecture exam in Immnuohematology and then a comprehensive final that will cover both Immunology and Immunohematology.
2.  A Lab Practical that is worth 200 points.
 
Mandatory Tutoring
If a student makes a grade below a 75% on any given quiz or exam they will be required to attend and show proof of a minimum of 1 hour of tutoring as directed by the instructor.
 

INCOMPLETE
Incompletes are granted only for emergency situations such as hospitalization of the student just prior to the final exam, serious injury to the student on the day of the final exam, etc. Incompletes will not be granted for situations involving vacation plans, transportation difficulties, appointments, etc. Students who need to request an incomplete must do so prior to the scheduled time of the final exam with appropriate documentation given to the instructor.

DROPPING/WITHDRAWING FROM CLASSES
No administrative drops/withdrawals will be initiated by program officials.  It is the responsibility of each student to drop or withdraw from a course. Students can drop a course via ACconnect, and must do so prior to the last day to drop/withdraw as posted on the Amarillo College Master Calendar. Students should be aware that failure to attend class does NOT result in being automatically dropped from a course, and WILL result in a grade of “F”. 

Students should be advised that they may repeat a MLAB course only one time, and may repeat no more than two courses while enrolled in the program. The term “repeat” shall be interpreted to mean re-enrollment following withdrawal, drop or an unsatisfactory grade from a class. Students who are forced to completely withdraw from the college during a given semester may re-apply for admission to the program. Once the student has actually begun the program, he/she must complete all MLAB major courses within 36 months.

Attendance

Regular attendance is necessary for satisfactory achievement. Therefore, it is the responsibility of the student to attend class. Attendance is included in the Work Ethic grade throughout the course which is a component of the overall grade for this course. Attendance includes arriving for class late and leaving early.  Less than 90% attendance in a course may result in failure of the course.  Students are required to notify faculty in advance of class absence.

Calendar

 

MLAB 2573: Immunology/Immunohematology  Course Schedule

 

Tentative Outline and Reading Schedule (Labs subject to change depending on availability and shipment of supplies):

Week

Day

Lecture

Lab

Exams

Assignment

Week 1

Monday

NO CLASS – Martin Luther King Day

Wednesday

Ch 1: Introduction to Immunity and the Immune System

Ch 2: Nature of Antigens and the MHC

Ch 8: Safety and Quality Management

Lab: Lab Safety and Infection Control

   

Week 2

Monday

Ch 3: Innate Immunity

Ch 4: Adaptive Immunity

Lab #1: Landsteiner Lab

Unit 1 Exam

(Ch 1-2 & 8)

11 am

Study questions for Lab #1

Wednesday

Ch 5: antibody Structure and Function

Ch 9: Principles of Serological Testing

Lab #2 Serial Dilutions

Quiz

Chapter 3-4

11 am

Study questions for Lab #2

Week 3

Monday

Ch 6: Cytokines

Ch 7: Complement System

Lab #3: Antigen-Antibody Specificity Reactions

Unit 2 Exam

(Ch 3-5 & 9)

11 am

Study questions for Lab #3

Wednesday

Ch 10: Precipitation and Agglutination Reactions

Ch 11: Labeled Immunoassays

Lab #4: Direct Antiglobulin Test

Quiz

Chapter 6-7

11 am

Study questions for Lab #4

Week 4

Monday

Ch 14: Hypersensitivity

Ch 15: Autoimmunity

Lab #5: Radial immunodiffusion

Lab #6 CRP

Unit 3 Exam

(Ch 6-7 & 10-11)

11 am

Study questions for Lab # 5 & 6

Wednesday

Ch 12: Molecular Diagnostic Techniques

Ch 13: Flow Cytometry and Laboratory Automation

Lab #7: Infectious Mononucleosis

Lab #8: Rheumatoid Arthritis

Quiz

Chapter 14-15

11 am

Study questions for Lab # 7 & 8

Week 5

Monday

Ch 16: Transplantation Immunology

Ch 17: Tumor Immunology

 

Lab #9: Ouchterlony technique

Unit 4 Exam

(Ch 14,15,12 &13)

10 am

Study questions for Lab # 9 &10

Wednesday

Ch 18: Immunoproliferative Diseases

Ch 19: Immunodeficiency Diseases

Lab #10: RPR

Quiz

Chapter 16-17

11 am

Study questions for Lab # 11 & 12

Week 6

Monday

Ch 20: Serological and Molecular Detection of Bacterial Infections

Ch 21: Spirochete Diseases

Lab #11: HIV Simulation

Unit 5 Exam

(Ch 16-19)

11 am

Study questions for Lab # 13

Wednesday

Ch 23: Serology and Molecular Detection of Viral Infections

Ch 24: Laboratory Diagnosis of HIV Infection

Lab Practical

Quiz

Chapter 20-21

11 am

 

Week 7

Monday

Ch 1: Red Cell and Platelet Preservation: Historical Perspectives, Review of Metabolism (pages 1-21)

Lab #1 Calibrating the Centrifuge

Lab #2: Cell Suspension

Lab #3: Grading Agglutination Reactions

Immuno Final Exam Comprehensive Given Monday of Week 7 at 11 am.

 

Wednesday

Ch 2: Basic Genetics (pages 26-42)

   

Study questions for Lab 1-3

Week 8

Monday

Ch 3: Fundamentals of Immunology (pages 45-74)

Lab #4: ABO Forwarding Typing

   

Wednesday

Ch 5: The Antiglobulin Test (pages 101-115)

Lab #4 cont.

Unit 1 Exam (Ch 1-3 & 5) Wednesday at 1 pm

Study questions for Lab #4

Spring Break

Week 9

Monday

Ch 6: The ABO Blood Group System (pages 119-146)

Lab #5: ABO Reverse Typing

 

Study questions for Lab #5

Wednesday

Ch 6 cont.

Lab #6 ABO Discrepancies

 

Study questions for Lab #6

Week 10

Monday

Ch 7: The Rh Blood Group System (pages 149-169)

Lab #7: Rh Blood Group Typing

 

Study questions for Lab #7

Wednesday

Ch 12: Other Technologies and Automation (pages 273-285)

Lab #7 cont

   

Week 11

Monday

Ch 8: Blood Group Terminology and the Other Blood Groups (pages 172-212)

Lab #8: Antibody Screening

Unit 2 Exam (Ch 6-7 and 12) Monday 11 am

Study questions for Lab #8

Wednesday

Ch 8 cont.

Lab #8 cont.

   

Week 12

Monday

Ch 9: Detection and Identification of Antibodies (pages 216-236)

Lab #9: Compatibility Testing

 

Study questions for Lab #9

Wednesday

Ch 10: Pretransfusion Testing

Lab #9 cont.

   

Week 13

Monday

Ch 13: Donor Screening and Component Preparation (pages 289-327)

Lab #10: Direct Antiglobulin Testing

Unit 3 Exam (Ch 8-10)  Monday 11 am

Study questions for Lab #10

Wednesday

Ch 13 cont.

Lab #11: Fetal Bleed – KB Stain

 

Study questions for Lab #11

Week 14

Monday

Ch 15: Transfusion Therapy (pages 352-365)

Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

   

Wednesday

Ch 16: Adverse Effects of Blood Transfusion (pages 367-388)

Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

   

Week 15

Monday

Ch 19: Hemolytic Disease of the Fetus and Newborn (HDFN)

Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

Unit 4 Exam (Ch 13, 15-16)  Monday 11 am

 

Wednesday

Ch 20: Autoimmune Hemolytic Anemias

Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

   

Week 16

     

Final Exam  Monday May 8 at 10 am

 

Additional Information

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Syllabus Created on:

01/11/18 2:21 PM

Last Edited on:

01/11/18 2:26 PM