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MLAB-2431-001 Immunohematology
Corequisite: MLAB 1235
A study of blood antigens and antibodies. Presents quality control, basic laboratory technique and safety. Includes the principles, procedures and clinical significance of test results in genetics, blood group systems, pre-transfusion testing, adverse effects of transfusions, donor selection and components and hemolytic disease of the newborn.
Student Resources Student Resources Website
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(4 sem hrs; 3 lec, 4 lab)
On Campus Course
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\ The supplies include the following:
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\\ Apply principles of safety, quality assurance and quality control in Immunohematology; evaluate specimen acceptability; describe blood group genetics, characteristics of the blood group systems, and the principles of immunology as they relate to immunohematology; list the requirements for the donation of blood; and describe the preparation, storage, and use of blood components; evaluate laboratory test results; select additional procedures to be performed; correlate test results with patient conditions; and describe the principles of and perform routine blood bank tests.
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Specific learning objectives for each section and each laboratory exercise are distributed as part of the lecture/lab handouts.
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INCOMPLETES
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Incompletes are granted only for emergency situations such as hospitalization of the student just prior to the final exam, serious injury to the student on the day of the final exam, etc. Incompletes will not be granted for situations involving vacation plans, transportation difficulties, appointments, etc. Students who need to request an incomplete must do so prior to the scheduled time of the final exam with appropriate documentation given to the instructor.
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DROPPING/WITHDRAWING FROM CLASSES
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No administrative drops/withdrawals will be initiated by program officials. It is the responsibility of each student to drop or withdraw from a course. Students can drop a course via WebAdvisor, and must do so prior to the last day to drop/withdraw as posted on the Amarillo College Master Calendar. Students should be aware that failure to attend class does NOT result in being automatically dropped from a course, and WILL result in a grade of “F”.
\ Students should be advised that they may repeat a MLAB course only one time, and may repeat no more than two courses while enrolled in the program. The term “repeat” shall be interpreted to mean re-enrollment following withdrawal, drop or an unsatisfactory grade from a class. Students who are forced to completely withdraw from the college during a given semester may re-apply for admission to the program. Once the student has actually begun the program, he/she must complete all MLAB major courses within 36 months.
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\ MLAB 2431: Immunohematology Course Schedule \\ \\ Tentative Outline and Reading Schedule (Labs subject to change depending on availability and shipment of supplies): \ | \
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\ Lab \ | \
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\ Assignment \ | \
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\ Week 1 \ | \
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\ Monday \ | \
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\ Ch 1: Red Cell and Platelet Preservation: Historical Perspectives, Review of Metabolism (pages 1-21) \ | \
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\ Lab Safety \ | \
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\ Wednesday \ | \
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\ Ch 2: Basic Genetics (pages 26-42) \\ \ | \
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\ Lab #1 Calibrating the Centrifuge \\ Lab #2: Cell Suspension \\ Lab #3: Grading Agglutination Reactions \ | \
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\ Study questions for Lab 1-3 \ | \
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\ Week 2 \ | \
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\ Monday \ | \
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\ Ch 3: Fundamentals of Immunology (pages 45-74) \\ \\ \ | \
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\ Lab #4: ABO Forwarding Typing \\ \ | \
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\ Study questions for Lab #4 \ | \
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\ Wednesday \ | \
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\ Ch 5: The Antiglobulin Test (pages 101-115) \\ \ | \
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\ Lab #4 cont. \ | \
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\ Unit 1 Exam (Ch 1-3 & 5) opens Friday 9 am and closes Monday 9 am \ | \
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\ Spring Break \ | \
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\ Week 3 \ | \
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\ Monday \ | \
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\ Ch 6: The ABO Blood Group System (pages 119-146) \ | \
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\ Lab #5: ABO Reverse Typing \\ \ | \
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\ Study questions for Lab #5 \ | \
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\ Wednesday \ | \
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\ Ch 6 cont. \ | \
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\ Lab #6 ABO Discrepancies \\ \ | \
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\ Study questions for Lab #6 \ | \
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\ Week 4 \ | \
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\ Monday \ | \
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\ Ch 7: The Rh Blood Group System (pages 149-169) \\ \ | \
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\ Lab #7: Rh Blood Group Typing \\ \ | \
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\ Study questions for Lab #7 \ | \
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\ Wednesday \ | \
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\ Ch 12: Other Technologies and Automation (pages 273-285) \\ \ | \
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\ Lab #7 cont \ | \
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\ Unit 2 Exam (Ch 6-7 and 12) opens Friday 9 am and closes Monday 9 am \ | \
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\ Week 5 \ | \
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\ Monday \ | \
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\ Ch 8: Blood Group Terminology and the Other Blood Groups (pages 172-212) \ | \
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\ Lab #8: Antibody Screening \\ \ | \
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\ Study questions for Lab #8 \ | \
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\ Wednesday \ | \
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\ Ch 8 cont. \ | \
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\ Lab #8 cont. \ | \
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\ Week 6 \ | \
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\ Monday \ | \
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\ Ch 9: Detection and Identification of Antibodies (pages 216-236) \ | \
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\ Lab #9: Compatibility Testing \\ \ | \
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\ Study questions for Lab #9 \ | \
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\ Wednesday \ | \
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\ Ch 10: Pretransfusion Testing \ | \
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\ Lab #9 cont. \ | \
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\ Unit 3 Exam (Ch 8-10) opens Friday 9 am and closes Monday 9 am \ | \
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\ Week 7 \ | \
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\ Monday \ | \
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\ Ch 13: Donor Screening and Component Preparation (pages 289-327) \ | \
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\ Lab #10: Direct Antiglobulin Testing \\ \ | \
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\ Study questions for Lab #10 \ | \
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\ Wednesday \ | \
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\ Ch 13 cont. \ | \
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\ Lab #11: Fetal Bleed – KB Stain \\ \ | \
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\ Study questions for Lab #11 \ | \
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\ Week 8 \ | \
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\ Monday \ | \
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\ Ch 15: Transfusion Therapy (pages 352-365) \ | \
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\ Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID) \\ \ | \
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\ Wednesday \ | \
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\ Ch 16: Adverse Effects of Blood Transfusion (pages 367-388) \ | \
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\ Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID) \\ \ | \
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\ Unit 4 Exam (Ch 13, 15-16) opens Friday 9 am and closes Monday 9 am \ | \
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\ Week 9 \ | \
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\ Monday \ | \
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\ Ch 19: Hemolytic Disease of the Fetus and Newborn (HDFN) \\ \\ \ | \
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\ Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID) \\ \ | \
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\ Wednesday \ | \
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\ Ch 20: Autoimmune Hemolytic Anemias \ | \
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\ Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID) \\ \ | \
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\ Week 10 \ | \
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\ Final Exam opens Monday 9am and closes Thursday 9 am \ | \
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