Radiochemistry and Radiopharmacy Syllabus for 2014-2015
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Instructor Information

Office Location

West Campus Allied Health 135

Office Hours

NUCLEAR MEDICINE TECHNOLOGY

Spring 2026 Schedule

Tamra Rocsko, MEd, CNMT, ARRT (N), Program Director

Office 354-6071  Cell 208-841-2533  Email: tlrocsko@actx.edu   

 

 

 

MONDAY

 

TUESDAY

 

WEDNESDAY

 

THURSDAY

 

FRIDAY

7:00

Clinical Rounds as needed

 

 

Clinical Rounds as needed

Clinical Rounds as needed

7:15

 

 

 

 

 

7:30

 

  

 

 

 

7:45

 

 

 

 

 

8:00 

Office/Advising 

Office/

Advising

 

Advising

Office/Advising

 

 

8:15

 

 

 

 

 

8:30  

 

 

 

 

 

8:45

 

 

 

 

 

9:00

 

 

 

    

 

9:15

 

 

 

 

 

9:30

 

 

 

 

 

9:45

 

 

 

 

 

10:00

 

Seminar

Radiopharm

 

 

10:15

 

Building AH 158

Building AH 158

 

 

10:30

 

10-3

10-3

 

 

10:45

 

 

 

 

 

11:00

 

 

 

 

 

11:15

 

 

 

 

 

11:30

 

 

 

 

 

11:45

 

 

 

 

 

12:00

 

 

 

 

Home

12:15

 

 

 

 

 

12:30

 

 

 

 

 

12:45

 

 

 

 

 

1:00

 

    

 

 

 

1:15

 

 

 

 

 

1:30

 

Office/Advising

 

 

 

1:45

 

 

 

 

 

2:00

 

 

 

 

 

2:15

 

 

 

 

 

2:30

 

 

 

 

 

2:45

 

 

Office/Advising

 

 

3:00

 

 

 

 

 

3:15

 

 

 

Home

 

3:30

 

 

 

       

 

4:00

Home

Home

Home

 

 

Course Information

Recording Policy

Disability Statement

Any student who, because of a disabling condition, may require some special arrangements in order to meet course requirements should contact disAbility Services (Student Service Center room 119, phone 371-5436) as soon as possible.

Statement for Mental Health and Advocacy & Resource Center:

As a student you may experience a range of issues that can cause barriers to learning, such as strained relationships, increased anxiety, alcohol/drug problems, feeling down, difficulty concentrating and/or lack of motivation. These mental health concerns or stressful events may lead to diminished academic performance or reduce a student's ability to participate in daily activities. Amarillo College offers services to assist you with addressing these and other concerns you may be experiencing. If you or someone you know are suffering from any of the aforementioned conditions, you can learn more about the broad range of confidential mental health services available on campus by calling the AC Counseling Center at 806-371-5900. The AC Counseling Center website is https://www.actx.edu/counseling/ . Also, if you are in need of social services (affordable housing, utilities, transportation, food, clothing, childcare, medical/dental/vision, legal), please call the AC Advocacy & Resource Center at 806-371-5439. The AC Advocacy & Resource Center website is https://www.actx.edu/arc

Amarillo College Tutoring for Success Policy:

Administrative Drop Policy

N/A

Student Withdrawal Procedures

N/A

Privacy Statement

The Amarillo College Privacy Policy is found at https://www.actx.edu/-amarillo-college-privacy-notice , and applies to all Amarillo College students.  If you have questions about this privacy statement or you believe that your personal information has been released without your consent, send email to humanresources@actx.edu .

Course

NMTT-2301-001 Radiochemistry and Radiopharmacy

Prerequisites

Prerequisite: CHEM 1305 or equivalent course

Course Description

Includes radioactive decay and production of radionuclides. Emphasis on radiopharmaceuticals and their ideal characteristics, biodistribution and clinical applications. Incorporates quality control tests and mathematical equations.

Student Resources Student Resources Website

Department Expectations

\N

Occupational License Disclaimer

Hours

(3 sem hrs; 2 lec, 2 lab)

Class Type

On Campus Course

Syllabus Information

Textbooks

\ Nuclear Medicine and PET/CT:  Technology and Techniques, 7th Edition, Christian

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\ Practical Mathematics in Nuclear Medicine Technology, Wells

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\ Review of Nuclear Medicine Technology, 4th Edition, Steves

Supplies

Scientific Calculator

The ability to create electronic documents through Google docs, word docs, PDF. Ability to scan/create/upload documents to blackboard

Student Performance

Workforce Education Course Manual (WECM) Course Description: Basic concepts of radiochemistry and radiopharmacy including the atomic structure, radioactive decay, and production of various radionuclides. Emphasis on radiopharmaceuticals and their ideal characteristics, biodistribution, and clinical applications; the various dosage forms in which they may be dispensed; quality control tests; and their formation and dispensing. End-of-Course Outcomes: Analyze the concepts of radiopharmacy; explain atomic structures and electronic configuration of atoms; describe various methods of radionuclide production and radiolabeling; interpret the mechanism of localization of various radiopharmaceuticals; cite quality control tests of various radiopharmaceuticals; identify radiation safety practices; and relate federal and state regulations governing the use of radiopharmaceuticals.

The Master Educational Plan of the Nuclear Medicine Technology Program requires these objectives to be met:

            Calculate radioactive decay using half-life.

            Analyze decay charts.

            Analyze universal decay chart.

            Perform pre-calibration calculations.

            Calculate specific concentration.

            Calculate dose volume.

            Calculate total activity needed to provide specific number of kits or doses.

            Calculate total volume to be added to kit.

            Calculate patient dosage based on activity per unit weight.

            Perform unit dose adjustments.

            Perform pediatric dose adjustments using Clark’s formula.

            Perform pediatric dose adjustments using body surface area (BSA).

            Perform pediatric dose adjustments using Talbot’s nomogram.

            Calculate minimum/maximum pediatric dosage.

            Calculate MAA lung perfusion particles.

            Calculate I-131 capsule dosage.

            Calculate Mo-99 generator yield based on efficiency of the generator.

            Calculate Mo-99/Tc99m generator yield based on decay.

            Calculate allowable Mo-99 content in generator eluate.

            Calculate allowable alumina content in generator eluate.

            Calculate eluate expiration time based on Mo-99 content.

            Perform chromatography calculations.

            Identify characteristics of radiopharmaceuticals from task analysis.

            Identify half-lives of radiopharmaceuticals listed on task analysis.

            Define valence state of Tc99m in relation to prescribed kits.

            Identify various types of generators.

            Identify chelating agents, reducing agents, additives, preservatives in kits.

            Describe the operations of a nuclear pharmacy.

            Identify diagnostic uses of radiopharmaceuticals in nuclear medicine.

            Identify therapeutic uses of radiopharmaceuticals.

            Describe quality control measures in the use of radiopharmaceuticals.

            Describe the use of monoclonal antibodies.

            Define molecular imaging.

            Write professional paper/engage in health sciences research methods.

            Pass major exams and other graded assignments with final grade of C or better.

Students Rights and Responsibilities

Student Rights and Responsibilities

Log in using the AC Connect Portal

In order to receive your AC Connect Email, you must log in through AC Connect at https://acconnect.actx.edu .

If you are an active staff or faculty member according to Human Resources, use "Exchange". All other students, use "AC Connect (Google) Email".

Expected Student Behavior

\ PHONES/PAGERS/LAPTOPS/OTHER TECHNOLOGICAL DEVICES

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\ Cell phones and other electronic devices are distractions within the learning environment.  For this reason, they are to be turned off and put away out of view upon entering the classroom.  They cannot be placed upon the desk but must be out of view.  Students may use a personal laptop computer for personal notetaking only. 

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\ STUDENTS WITH DISABILITIES

\

\ Any student, who, because of a disabling condition, may require some special arrangements in order to meet course requirements.

\

\ Contact disability Services at 345-5639 for any special need.

\

\ GRIEVANCE PROCEDURE

\

\ A student who may have concerns or problems with the course or course instructor should make every attempt to resolve the problem with the course instructor.  In the event that it is not successful, the student may appeal the decision of the instructor to the program director, then the Dean of the Health Sciences Division, the Vice President of Academic Affairs, and the College President, in that order.

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\ STUDENTS RIGHTS/RESPONSIBILITIES

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\ Please refer to the Students Rights and Responsibilities publication of Amarillo College (Web site or hard copy available in student services).

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\ Students are responsible for maintaining all aspects set forth within the publication so that professionalism is maintained.

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\ THE CLASSROOM ENVIRONMENT

\

\ Mutual respect is foremost in this classroom.  Please make yourself at home within the classroom, regarding your peers and instructors with utmost respect.

\

\ Students should feel free to express ideas/thoughts without making others in the classroom feel uncomfortable.

\

\ AC ONLINE COMMUNICATION

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\ Use your personal account to check grades, emails, download course lecture material, etc. 

\

\ Students are responsible for checking their accounts daily so that communication about program/course information is current.

\

\ Students may also use any of the instructor contact information provided on the syllabus or classroom schedule provided each semester.

Grading Criteria

REQUIRED ASSIGNMENTS

Grading Criteria:

The course will consist of the following activities to be scored for course credit:

  1. Assignments/Quizzes/DB/Presentations (15%) Major Exams (85%) Comprehensive Final Exam (counts as major exam). 
  2. Research Paper-will be graded per rubric and count as major exam grade.
  3. A passing grade for each exam is expected.  If a student does not pass an exam, the student is assigned an "at risk score", prompting them to engage in mandatory remediation (review) for the exam that the student did not pass.  If a second exam is not passed, the student will be assigned an automatic course grade of "F", and must enroll in the course at a later date, causing the student to not graduate on time. If a student fails one test, and then fails the final, it will be addressed case by case. 
  4. The course content is comprehensive in nature so that students are expected to carry information from one semester to the next.
  5. NOTE:  A study guide, chapter objectives and key terms will be completed out of class and will be used to prepare for exams utilizing textbooks and powerpoint lecture.  This study guide with chapter objectives and key terms will be utilized and turned in by each student prior to each exam.  Failure to turn in the study guide/key terms/objectives will result in a drop in a letter grade  (10 points) for each exam that the notes are linked to. *NOTE* ALL math assignments will be counted as a grade worth 100 points, however these are also you study guide to your math exams; therefore if a math assignment is not turned a grade of zero will be given as well as a letter grade drop (10 points) on the exam it is linked to. Math assignments must show work or they will be counted as wrong. 
  6. Any assignments or quizzes missed will result in a zero.
  7. A student may not make over a 100 on an exam even with bonus points. Bonus points may not be applied to another exam.
  8. NOTE: Math section assignments will be completed in and out of class and will be used to prepare for exams utilizing textbooks, videos, and lecture/lab.  

FINAL GRADE EVALUATION (NO ROUNDING of grade)

A= 94.5-100            C=74.5-84.4

B=84.5-94.4            F=less than 74.5

MAKE-UP POLICY

If a student is absent on the day of a major exam, quiz, or the day that a topic outline is due, the work will be graded as follows:

  1. In order to be fair to students who take scheduled exams at the designated time, makeup exams will lose 15% of the original value.
  2. Major exams must be made up within one school day.
  3. Class activities cannot be made up.  It is the responsibility of the student to contact the instructor to acquire information on missed content.
  4. NOTE:  Other arrangements may be made with instructor’s permission on a case-by-case basis.  It is the sole responsibility of the student to communicate the need for other options regarding make-up policies.

Attendance

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\

\ Attendance Policy

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\ Regular attendance is necessary for satisfactory achievement.  It is the responsibility of the student to attend class so that learning objectives are met successfully.  Prompt arrival is expected.  Attendance will be recorded.

\

\  

\

\ MAKE-UP POLICY

\

\ If a student is absent on the day of a major exam or class activity, the work will be graded as follows:

\
    \
  1. \ In order to be fair to students who take scheduled exams at the designated time, makeup exams will lose 15% of the original value.
  2. \
  3. \ Major exams must be made up within one school day.
  4. \
  5. \ Class activities cannot be made up.  It is the responsibility of the student to get in touch with the instructor to acquire information if absent from class.
  6. \
  7. \ NOTE:  Other arrangements may be made with instructor’s permission on a case-by-case basis.  It is the sole responsibility of the student to communicate the need for other options regarding make-up policies.
  8. \

Calendar

Outline

Week one Jan 21: Syllabi, health science research, Kaki Hoover presentation on research.

Week two Jan 28: Pharmacy tours

Week three Feb 4: Class activity (over pharmacy). Print and bring to class. Reading assignment big text ch 6. RB ch 3 and ch 8. In class: Pharmacy and generators.

Week four Feb 10 11:59 pm: DB 1 (Discuss/Describe quality control measures in the use of radiopharmaceuticals. (for connection to clinical setting, what happens if no QC is done on a kit, or QC doesn't pass and the dose is still sent out, how does this affect your images?)  Go to page 29 in your review book and discuss the FORMULA and definition for RF value.  What 3 things are we looking for (purity/impurity)? What is free Tc vs. straight Tc? What 3 forms of Tc are present in an RP kit? Radiochemical vs. radionuclidic purity, how are they different and how to you check for it) Generator paper (how it works, difference between wet and dry).

Feb 11: Group presentations (Discuss cardiac drugs used in NM: dipyridamole, adenosine, dobutamine, aminophylline, regadenoson, beta blockers, atropine, NTG spray, paste, pill, and drip. Include other names, what it does, plasma half life, etc. Discuss EDTA, Lidocaine, Lidocaine (EMLA) cream, ACD solution, heparin, ascorbic acid, hetastarch.) Class: Identify characteristics of radiopharmaceuticals from task analysis. Define valence state of Tc99m in relation to prescribed kits. Identify chelating agents, reducing agents, additives, preservatives in kits. Identify diagnostic uses of radiopharmaceuticals in nuclear medicine.

Week five Feb 17 11:59pm: half life quiz, DB2 (Define and discuss valence state of Tc99m in relation to prescribed kits. Identify and discuss chelating agents, reducing agents, additives, preservatives in kits. Discuss adverse reactions/pyrogens. What additives may be used (stabilizers, preservatives, etc.) and why. What kits require special prep like refrigeration, cooking, light sensitive, stabilizers, etc.)

Feb 18 class: Identify therapeutic uses of radiopharmaceuticals. Describe the use of monoclonal antibodies. Define molecular imaging.

Week six Feb 24 11:59 pm: DB 3 (Discuss methods of labeling. Cold kit vs. hot kit. What makes it a radiopharmaceutical (radionuclide vs. radiopharmaceutical)? Reducing the valence state of Tc from 7 to 4....why? What about Sulfur Colloid? What reducing agents are used?)

Feb 25: Group presentations (Discuss general NM drugs: captopril, enaloprilat, furosemide, insulin, acetazolamide, cholecystokinen/sincalide/CCK, morphine, cimetidine/ranitidine/famotidine. Other names, what procedure its used for and why. Discuss contrast media, Lugol's solution/SSKI, TSH, recombinant human TSH. Do you give contrast media on the same days as NM scans? What about Thyroid uptake and imaging?) Class: PET RP’s

Week seven March 3  11:59 pm: DB 4 (Identify and discuss therapeutic uses of radiopharmaceuticals. Discuss the use of monoclonal antibodies. Discuss molecular imaging.), PET paper (how F 18 RP's are produced as well as Rb 82 (generator/reactor/cyclotron, etc) Discuss PET RP's. Are all PET RP's tagged? Kev?)

March 4: Class activity TBA

Week eight March 10  11:59pm: Quiz, DB 5 (Discuss Iodine RP's including those used for therapy. Are they tagged? Discuss all other Therapy Nuclides, (excluding I-131). Are they tagged? Discuss miscellaneous RP's (RBC and WBC....what g's do you use for centrifuge or do you even use a centrifuge and when is hetastarch appropriate, Gallium, Indium, Thallium, Xe 133. (Basically NON Tc99, PET, Therapy, and Iodine RP's). Are they tagged?), Obj/key terms/study guide

March 11: Exam (in class or testing center TBA)

Week nine spring break March 16-20

Week eleven March 25: class math section 19

March 31 11:59 pm section 19 math

April 1 exam section 19

April 7 11:59 pm section 1-3 and 16 math

April 8 exam section 1-3, 16, and 19 math

April 14 11:59pm section 15, 17, and 18

April 15 exam section 1-3, 16, 15, 17, 18, and 19

April 21 11:59 section 4-12, and 14

April 22 exam 4-12, 14, 1-3, 16, 15, 17, 18, 19

April 29 Research papers due

May 6 review challenge TBA

May 12 final exam

Note:  The instructor reserves the right to change/alter this calendar as student learning needs arise.

 

Additional Information

The course content is aligned with the Master Educational Plan of the Nuclear Medicine Technology Program at Amarillo College.

In addition, the lecture content aligns with the task analysis of the Nuclear Medicine Technology Certification Board and The American Registry of Radiologic Technologists.

The Nuclear Medicine Technology program at Amarillo College is fully accredited by the Joint Review Committee on Education in Nuclear Medicine Technology.

Additional Information:

AC-Connect Online (BlackBoard)) Communication-www.actx.edu

This is the major source for program communication.

Students will use the AC Online personal account to check grades, e-mails, etc.  Students are responsible for checking their accounts daily so that communication about program/course information is current.

            https://www.actx.edu/resources/

This website was created to assist Amarillo College employees and students. Many times, students come to us with individual concerns/situations that need to be addressed in order for the student to be successful in school.

This website can be used to find those needed resources for our students and their families. Feel free to copy any of this information for a student and to refer students as needed.

Our goal is to provide as much information as possible for employees and students to be able to access campus and community resources when needed. There are many more resources in this community that are not listed on these pages. Some of these agencies and programs will change; so if you call and cannot get assistance or cannot access a broken link, please contact me for more updated information.

This website will be updated as often as possible; therefore, most will be current. If the resources listed do not serve the needs you have or if you have any questions concerning this website, please call or email:  Jordan Fajardo, LMSW, Coordinator of Social Services, 806-371-5439, j0333462@actx.edu.

Student Injuries Information (class and clinical)

https://www.actx.edu/allied_health/index.php?module=article&id=33

Syllabus Created on:

11/30/-1 12:00 AM

Last Edited on:

11/30/-1 12:00 AM