Immunology/Immunohematology Syllabus for 2015-2016
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Instructor Information

Office Location

West Campus Allied Health 151A

Office Hours

by appointment

Course Information

Recording Policy

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Administrative Drop Policy

N/A

Student Withdrawal Procedures

N/A

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Course

MLAB-2573-001 Immunology/Immunohematology

Prerequisites

Corequisite: MLAB 1211

Course Description

An introduction to the theory and application of basic immunology, including the immune response, principles of antigen-antibody reactions, and the principles of serological procedures as well as quality control, quality assurance and safety. In addition, a study of blood antigens and antibodies. Includes the principles, procedures and clinical significance of test results in genetics, blood group systems, pre-transfusion testing, adverse effects of transfusions, donor selection and components, and hemolytic disease of the newborn.

Student Resources Student Resources Website

Department Expectations

\N

Occupational License Disclaimer

Hours

(5 sem hrs; 3 lec, 8 lab)

Class Type

On Campus Course

Syllabus Information

Textbooks

Modern Blood Banking and Transfusion Practices, 6th Ed., Harmening, FA Davis, 2012, ISBN: 13:0-8036-2682-9
Immunology and Serology in Lab Medicine, 5th Ed, Turgeon, CV Mosley, 2014, ISBN13: 978-0323085182

Supplies

The supplies include the following:

  • Textbook(s) and lab manual
  • Computer
  • Internet access
  • Disposable lab coat
  • Facial shields
  • Sharpies
  • Pens/pencils/paper

Student Performance

\ COURSE OUTCOMES

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\ Apply principles of safety, quality assurance and quality control in Immunohematology; evaluate specimen acceptability; describe blood group genetics, characteristics of the blood group systems, and the principles of immunology as they relate to immunohematology; list the requirements for the donation of blood; and describe the preparation, storage, and use of blood components; evaluate laboratory test results; select additional procedures to be performed; correlate test results with patient conditions; and describe the principles of and perform routine blood bank tests.

\ Specific learning objectives for each section and each laboratory exercise are distributed as part of the lecture/lab handouts.
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Students Rights and Responsibilities

Student Rights and Responsibilities

Log in using the AC Connect Portal

In order to receive your AC Connect Email, you must log in through AC Connect at https://acconnect.actx.edu .

If you are an active staff or faculty member according to Human Resources, use "Exchange". All other students, use "AC Connect (Google) Email".

Expected Student Behavior

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\ ACADEMIC DISHONESTY
\ Academic dishonesty shall constitute a violation of the college rules and regulations and is punishable as prescribed by Amarillo College Board policies. Academic dishonesty shall include, but is not limited to, cheating on a test/quiz/assignment, plagiarism, and collusion. Cheating shall include:
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  • \ Copying from another student's test/assignment paper.
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  • \ Using test materials not authorized by the person administering the test/assignment (ex: notes, books, etc).
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  • \ Collaborating with or seeking aid from another student during a test/assignment without permission from the test/assignment administrator/instructor.
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  • \ Knowingly using, buying, selling, stealing, or soliciting, in whole or in part, the contents of an administered/unadministered test/assignment.
  • \
  • \ The unauthorized transporting or removal, in whole or in part, of the contents of the administered/unadministered test/assignment.
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  • \ Substituting for another student, or permitting another student to substitute for one's self, to take a test/assignment.
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  • \ Bribing another person to obtain an administered/unadministered test/assignment or information about an administered/unadministered test/assignment.
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\ Plagiarism shall be defined as the appropriating, buying, receiving as a gift, or obtaining by any means another's work and the unacknowledged submission or incorporation of it in one's own written work.
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\ Collusion shall be defined as the unauthorized collaboration with another person in preparing written work for fulfillment of course requirements.
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\ WORK ETHICS
\ Amarillo College and the Medical Laboratory Technology program are committed to developing knowledge, skills, attitudes, and behaviors in students so that they can obtain entry-level employment and advance in their chosen profession. Great measures are taken to ensure that the curriculum is updated and that equipment is purchased and kept at industry level, as much as possible. Program Advisory committees meet annually to ensure that the curriculum meets the needs of the local medical community as well as the program's national accrediting agency.
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\ We are committed to providing these things to ensure that a graduate has the skills and knowledge to obtain and advance in their chosen profession. Therefore, professional education must address more than academic and skills training in order to meet this challenge. Business and industry state that their greatest need is for employees who possess strong work ethics. Therefore, we accept the challenge of providing not only academic and hands-on training but also work ethics training to students. The work ethics program is important because it provides the link between academic knowledge, skills training and successful employment in the workforce. The program focuses on those behaviors expected in a professional environment.
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\ The following work ethics have been identified as being most important to professional employers, and will be covered and evaluated on a weekly basis, each semester, throughout the program:
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  • \ Attendance
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  • \ Character
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  • \ Teamwork
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  • \ Appearance
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  • \ Attitude
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  • \ Productivity
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  • \ Organization
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  • \ Communication
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  • \ Cooperation
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  • \ Respect
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\ NOTE: If a student is absent during a scheduled lecture/lab period, he/she cannot be awarded points for work ethics during that missed lecture/lab period.
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\ CELLULAR TELEPHONES AND PAGERS
\ Cellular telephones and pagers are disruptive during lecture and lab sessions. Cellular telephones and pagers should be turned-off during class time, or set on vibrate or "blink" during class time. If the student anticipates an emergency during class time, they should leave the number for the Student Services Office with their contact. The number is 371-5300.
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\ Text/Instant Messaging is NOT permitted when lectures and labs are in session.  It is disruptive and disrespectful to fellow students and the course instructor. Students who are caught engaging in either of these will be subject to disciplinary action including, but not limited to:
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  1. \ Being asked to leave class for the remainder of the day
  2. \
  3. \ Mandatory conference with the Assistant Dean of Career and Technical Programs
  4. \
  5. \ Conference with the Dean of Students and a permanent entry in the student's official program record
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    \ The ONLY exception that will be made is if the student has discussed the situation with their instructor beforehand, and ONLY for emergency purposes.
  6. \
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\ GRIEVANCE PROCEDURE  If a student is having a problem with the course policies or the instructor, he or she should first try and resolve any such problems through the instructor. If the problem is not resolved, the student may proceed to the Program Director (Jan Martin), the Dean of Health Sciences (Mark Rowh), Vice President of of Academic Affairs (Dr Russell Lowery-Hart), and the College President (Dr Paul Matney), IN THAT ORDER.
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Grading Criteria

The lecture and laboratory components of this course will be weighted as follows:
Lecture = 75% of the total grade
Lab = 15% of the total grade
Work Ethics = 10% of the total grade
 
The grading scale used for this course is as follows:
A = 90.0% - 100.0% of the total points possible for the course 
B = 80.0% - 89.9% of the total points possible for the course
C = 70.0% - 79.9% of the total points possible for the course
F = 69.9% or less of the total points possible for the course
NOTE: A grade of 'D' is not possible
 
Examinations and quizzes may not be made up. Students will be given each unit exam and final exam in class.
 
Students are not allowed to make up the labs. The study questions for each lab are due the day the lab is performed, if that lab is missed the study questions will only be worth half the original points.
 
Major examinations will be given over the lecture and reading material. A comprehensive final will be given at the end of this course. Quizzes may be given, announced or unannounced, at any time, so the student is advised to complete all assignments in a timely manner in order to be successful on quizzes. No credit will be given for assignments, notebooks, etc..., turned in after the specified date. A total accumulative point system is used to calculate the final grade average and is comprised of the following:
1.  eNotebooks are worth a possible total of 50 points.
2.  Major Lecture Examinations (100 points possible per exam)
3.  Lab procedures and study questions (10-25 points, possible)
4.  Quizzes (10-25 points possible, each)
5.  Work Ethics: (0 - 10 possible per class day, based on work ethic discussions, assignments, and student demonstration of positive work ethic qualities, as evaluated by their instructor(s)
 
There are two final exams:
1.  A Lecture exam that consists of 150 multiple choice questions and is worth 150 points.
2.  A Lab Pracical that is worth 200 points.
 

INCOMPLETES
Incompletes are granted only for emergency situations such as hospitalization of the student just prior to the final exam, serious injury to the student on the day of the final exam, etc. Incompletes will not be granted for situations involving vacation plans, transportation difficulties, appointments, etc. Students who need to request an incomplete must do so prior to the scheduled time of the final exam with appropriate documentation given to the instructor.

DROPPING/WITHDRAWING FROM CLASSES
No administrative drops/withdrawals will be initiated by program officials.  It is the responsibility of each student to drop or withdraw from a course. Students can drop a course via WebAdvisor, and must do so prior to the last day to drop/withdraw as posted on the Amarillo College Master Calendar. Students should be aware that failure to attend class does NOT result in being automatically dropped from a course, and WILL result in a grade of “F”. 

Students should be advised that they may repeat a MLAB course only one time, and may repeat no more than two courses while enrolled in the program. The term “repeat” shall be interpreted to mean re-enrollment following withdrawal, drop or an unsatisfactory grade from a class. Students who are forced to completely withdraw from the college during a given semester may re-apply for admission to the program. Once the student has actually begun the program, he/she must complete all MLAB major courses within 36 months.

Attendance

\ Regular attendance is necessary for satisfactory achievement. Therefore, it is the responsibility of the student to attend class. Attendance is included in the Work Ethic grade throughout the course which is a component of the overall grade for this course. Attendance includes arriving for class late and leaving early.

Calendar

 

MLAB 2573: Immunology/Immunohematology  Course Schedule

 

Tentative Outline and Reading Schedule (Labs subject to change depending on availability and shipment of supplies):

 

Week

Day

Lecture

Lab

Exams

Assignment

Week 1

 

Monday

NO CLASS – Martin Luther King Day

Wednesday

Ch 1: An Overview of Immunology,

Ch 2: Antigens and Antibodies,

Ch 8: Basic Serologic Laboratory Technique

Ch 9: Point-of-Care Testing

Lab: Lab Safety and Infection Control

 

 

Week 2

Monday

Ch 3: Granulocytes and Monocytes

Ch 4: Lymphocytes and Plasma Cells,

Ch 5: Soluble Mediators of the Immune System

Lab #1: Landsteiner Lab

Unit 1 Exam (Ch 1-2 & 8-9) 10 am

Study questions for Lab #1

Wednesday

Ch 10: Agglutination Methods,

Ch 11: Electrophoresis Techniques

Lab #2 Serial Dilutions

 

Study questions for Lab #2

Week 3

Monday

Ch 16: A Primer on Vaccines

Ch 17: Streptococcal Infections

Ch 18: Syphilis   

Lab #3: Antigen-Antibody Specificity Reactions

 

Unit 2 Exam (Ch 3-5 & 10-11) 10 am

Study questions for Lab #3

Wednesday

Ch 19: Vector-Borne Diseases

Ch 12: Labeling Techniques in Immunoassay

Lab #4: Direct Antiglobulin Test

 

Study questions for Lab #4

Week 4

Monday

Ch 21: Cytomegalovirus

Ch 22: Infectious Mononucleosis

Ch 23: Viral Hepatitis

Lab #5: Radial immunodiffusion

 

Unit 3 Exam (Ch 16-19 & 12) 10 am

Study questions for Lab # 5 & 6

Wednesday

Ch 24: Rubella Infection

Ch 25: Acquired Immunodeficiency Syndrome

Lab #6 CRP

Lab #7: Infectious Mononucleosis

Lab #8: Rheumatoid Arthritis

 

 

Study questions for Lab # 7 & 8

Week 5

Monday

26: Hypersensitivity Reactions

Ch 27: Immunoproliferative Disorders

Ch 28: Autoimmune Disorders

 

Lab #9: Ouchterlony technique

 

Unit 4 Exam (Ch 21-25) 10 am

Study questions for Lab # 9 &10

Wednesday

Ch 29: Systemic Lupus Erythematosus

Ch 30: Rheumatoid Arthritis

Lab #10: RPR

 

 

Study questions for Lab # 11 & 12

Week 6

Monday

Ch 31: Solid Organ Transplantation

Ch 32: Bone Marrow Transplantation

Ch 33: Tumor Immunology

Lab #11: HIV Simulation

 

Unit 5 Exam (Ch 26-30) 10 am

Study questions for Lab # 13

Wednesday

Ch 13: Automated Procedures

Ch 14: Molecular Techniques

 

Lab Practical

 

 

 

Week 7

Monday

Ch 1: Red Cell and Platelet Preservation: Historical Perspectives, Review of Metabolism (pages 1-21)

Lab #1 Calibrating the Centrifuge

Lab #2: Cell Suspension

Lab #3: Grading Agglutination Reactions

Immuno Final Exam Comprehensive Given Monday of Week 7 at 10 am.

 

Wednesday

Ch 2: Basic Genetics (pages 26-42)

 

 

 

Study questions for Lab 1-3

Week 8

Monday

Ch 3: Fundamentals of Immunology (pages 45-74)

Lab #4: ABO Forwarding Typing

 

 

 

Wednesday

Ch 5: The Antiglobulin Test (pages 101-115)

 

Lab #4 cont.

Unit 1 Exam (Ch 1-3 & 5) Wednesday at 1 pm

Study questions for Lab #4

Spring Break

Week 9

Monday

Ch 6: The ABO Blood Group System (pages 119-146)

Lab #5: ABO Reverse Typing

 

 

Study questions for Lab #5

Wednesday

Ch 6 cont.

Lab #6 ABO Discrepancies

 

 

Study questions for Lab #6

Week 10

Monday

Ch 7: The Rh Blood Group System (pages 149-169)

 

Lab #7: Rh Blood Group Typing

 

 

Study questions for Lab #7

Wednesday

Ch 12: Other Technologies and Automation (pages 273-285)

 

Lab #7 cont

 

 

Week 11

Monday

Ch 8: Blood Group Terminology and the Other Blood Groups (pages 172-212)

Lab #8: Antibody Screening

 

Unit 2 Exam (Ch 6-7 and 12) Monday 10 am

Study questions for Lab #8

Wednesday

Ch 8 cont.

Lab #8 cont.

 

 

Week 12

Monday

Ch 9: Detection and Identification of Antibodies (pages 216-236)

Lab #9: Compatibility Testing

 

 

Study questions for Lab #9

Wednesday

Ch 10: Pretransfusion Testing

Lab #9 cont.

 

 

Week 13

Monday

Ch 13: Donor Screening and Component Preparation (pages 289-327)

Lab #10: Direct Antiglobulin Testing

 

Unit 3 Exam (Ch 8-10)  Monday 10 am

Study questions for Lab #10

Wednesday

Ch 13 cont.

Lab #11: Fetal Bleed – KB Stain

 

 

Study questions for Lab #11

Week 14

Monday

Ch 15: Transfusion Therapy (pages 352-365)

Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

 

 

Wednesday

Ch 16: Adverse Effects of Blood Transfusion (pages 367-388)

Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

 

 

Week 15

Monday

Ch 19: Hemolytic Disease of the Fetus and Newborn (HDFN)

 

Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

Unit 4 Exam (Ch 13, 15-16)  Monday 10 am

 

Wednesday

Ch 20: Autoimmune Hemolytic Anemias

Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)

 

 

 

Week 16

 

 

 

Final Exam  Monday May

 

Additional Information

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Syllabus Created on:

11/30/-1 12:00 AM

Last Edited on:

11/30/-1 12:00 AM