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MLAB-2573-001 Immunology/Immunohematology
Corequisite: MLAB 1211
An introduction to the theory and application of basic immunology, including the immune response, principles of antigen-antibody reactions, and the principles of serological procedures as well as quality control, quality assurance and safety. In addition, a study of blood antigens and antibodies. Includes the principles, procedures and clinical significance of test results in genetics, blood group systems, pre-transfusion testing, adverse effects of transfusions, donor selection and components, and hemolytic disease of the newborn.
Student Resources Student Resources Website
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(5 sem hrs; 3 lec, 8 lab)
On Campus Course
The supplies include the following:
\ COURSE OUTCOMES
\\ Apply principles of safety, quality assurance and quality control in Immunohematology; evaluate specimen acceptability; describe blood group genetics, characteristics of the blood group systems, and the principles of immunology as they relate to immunohematology; list the requirements for the donation of blood; and describe the preparation, storage, and use of blood components; evaluate laboratory test results; select additional procedures to be performed; correlate test results with patient conditions; and describe the principles of and perform routine blood bank tests.
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Specific learning objectives for each section and each laboratory exercise are distributed as part of the lecture/lab handouts.
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If you are an active staff or faculty member according to Human Resources, use "Exchange". All other students, use "AC Connect (Google) Email".
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INCOMPLETES
Incompletes are granted only for emergency situations such as hospitalization of the student just prior to the final exam, serious injury to the student on the day of the final exam, etc. Incompletes will not be granted for situations involving vacation plans, transportation difficulties, appointments, etc. Students who need to request an incomplete must do so prior to the scheduled time of the final exam with appropriate documentation given to the instructor.
DROPPING/WITHDRAWING FROM CLASSES
No administrative drops/withdrawals will be initiated by program officials. It is the responsibility of each student to drop or withdraw from a course. Students can drop a course via WebAdvisor, and must do so prior to the last day to drop/withdraw as posted on the Amarillo College Master Calendar. Students should be aware that failure to attend class does NOT result in being automatically dropped from a course, and WILL result in a grade of “F”.
Students should be advised that they may repeat a MLAB course only one time, and may repeat no more than two courses while enrolled in the program. The term “repeat” shall be interpreted to mean re-enrollment following withdrawal, drop or an unsatisfactory grade from a class. Students who are forced to completely withdraw from the college during a given semester may re-apply for admission to the program. Once the student has actually begun the program, he/she must complete all MLAB major courses within 36 months.
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MLAB 2573: Immunology/Immunohematology Course Schedule
Tentative Outline and Reading Schedule (Labs subject to change depending on availability and shipment of supplies):
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Week |
Day |
Lecture |
Lab |
Exams |
Assignment |
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Week 1
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Monday |
NO CLASS – Martin Luther King Day |
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Wednesday |
Ch 1: An Overview of Immunology, Ch 2: Antigens and Antibodies, Ch 8: Basic Serologic Laboratory Technique Ch 9: Point-of-Care Testing |
Lab: Lab Safety and Infection Control |
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Week 2 |
Monday |
Ch 3: Granulocytes and Monocytes Ch 4: Lymphocytes and Plasma Cells, Ch 5: Soluble Mediators of the Immune System |
Lab #1: Landsteiner Lab |
Unit 1 Exam (Ch 1-2 & 8-9) 10 am |
Study questions for Lab #1 |
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Wednesday |
Ch 10: Agglutination Methods, Ch 11: Electrophoresis Techniques |
Lab #2 Serial Dilutions |
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Study questions for Lab #2 |
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Week 3 |
Monday |
Ch 16: A Primer on Vaccines Ch 17: Streptococcal Infections Ch 18: Syphilis |
Lab #3: Antigen-Antibody Specificity Reactions
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Unit 2 Exam (Ch 3-5 & 10-11) 10 am |
Study questions for Lab #3 |
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Wednesday |
Ch 19: Vector-Borne Diseases Ch 12: Labeling Techniques in Immunoassay |
Lab #4: Direct Antiglobulin Test |
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Study questions for Lab #4 |
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Week 4 |
Monday |
Ch 21: Cytomegalovirus Ch 22: Infectious Mononucleosis Ch 23: Viral Hepatitis |
Lab #5: Radial immunodiffusion
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Unit 3 Exam (Ch 16-19 & 12) 10 am |
Study questions for Lab # 5 & 6 |
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Wednesday |
Ch 24: Rubella Infection Ch 25: Acquired Immunodeficiency Syndrome |
Lab #6 CRP Lab #7: Infectious Mononucleosis Lab #8: Rheumatoid Arthritis
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Study questions for Lab # 7 & 8 |
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Week 5 |
Monday |
26: Hypersensitivity Reactions Ch 27: Immunoproliferative Disorders Ch 28: Autoimmune Disorders |
Lab #9: Ouchterlony technique
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Unit 4 Exam (Ch 21-25) 10 am |
Study questions for Lab # 9 &10 |
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Wednesday |
Ch 29: Systemic Lupus Erythematosus Ch 30: Rheumatoid Arthritis |
Lab #10: RPR
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Study questions for Lab # 11 & 12 |
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Week 6 |
Monday |
Ch 31: Solid Organ Transplantation Ch 32: Bone Marrow Transplantation Ch 33: Tumor Immunology |
Lab #11: HIV Simulation
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Unit 5 Exam (Ch 26-30) 10 am |
Study questions for Lab # 13 |
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Wednesday |
Ch 13: Automated Procedures Ch 14: Molecular Techniques
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Lab Practical
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Week 7 |
Monday |
Ch 1: Red Cell and Platelet Preservation: Historical Perspectives, Review of Metabolism (pages 1-21) |
Lab #1 Calibrating the Centrifuge Lab #2: Cell Suspension Lab #3: Grading Agglutination Reactions |
Immuno Final Exam Comprehensive Given Monday of Week 7 at 10 am. |
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Wednesday |
Ch 2: Basic Genetics (pages 26-42)
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Study questions for Lab 1-3 |
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Week 8 |
Monday |
Ch 3: Fundamentals of Immunology (pages 45-74) |
Lab #4: ABO Forwarding Typing
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Wednesday |
Ch 5: The Antiglobulin Test (pages 101-115)
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Lab #4 cont. |
Unit 1 Exam (Ch 1-3 & 5) Wednesday at 1 pm |
Study questions for Lab #4 |
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Spring Break |
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Week 9 |
Monday |
Ch 6: The ABO Blood Group System (pages 119-146) |
Lab #5: ABO Reverse Typing
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Study questions for Lab #5 |
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Wednesday |
Ch 6 cont. |
Lab #6 ABO Discrepancies
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Study questions for Lab #6 |
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Week 10 |
Monday |
Ch 7: The Rh Blood Group System (pages 149-169)
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Lab #7: Rh Blood Group Typing
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Study questions for Lab #7 |
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Wednesday |
Ch 12: Other Technologies and Automation (pages 273-285)
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Lab #7 cont |
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Week 11 |
Monday |
Ch 8: Blood Group Terminology and the Other Blood Groups (pages 172-212) |
Lab #8: Antibody Screening
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Unit 2 Exam (Ch 6-7 and 12) Monday 10 am |
Study questions for Lab #8 |
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Wednesday |
Ch 8 cont. |
Lab #8 cont. |
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Week 12 |
Monday |
Ch 9: Detection and Identification of Antibodies (pages 216-236) |
Lab #9: Compatibility Testing
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Study questions for Lab #9 |
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Wednesday |
Ch 10: Pretransfusion Testing |
Lab #9 cont. |
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Week 13 |
Monday |
Ch 13: Donor Screening and Component Preparation (pages 289-327) |
Lab #10: Direct Antiglobulin Testing
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Unit 3 Exam (Ch 8-10) Monday 10 am |
Study questions for Lab #10 |
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Wednesday |
Ch 13 cont. |
Lab #11: Fetal Bleed – KB Stain
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Study questions for Lab #11 |
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Week 14 |
Monday |
Ch 15: Transfusion Therapy (pages 352-365) |
Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID) |
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Wednesday |
Ch 16: Adverse Effects of Blood Transfusion (pages 367-388) |
Mock Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID) |
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Week 15 |
Monday |
Ch 19: Hemolytic Disease of the Fetus and Newborn (HDFN)
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Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID) |
Unit 4 Exam (Ch 13, 15-16) Monday 10 am |
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Wednesday |
Ch 20: Autoimmune Hemolytic Anemias |
Practical (1 DAT, 1 Crossmatch, and 1 Antibody ID)
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Week 16 |
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Final Exam Monday May |
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