Compounding Sterile Preparations Syllabus for 2021-2022
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PHRA-1445-002 Compounding Sterile Preparations


Prerequisites: PHRA 1301 and PHRA 1309

Course Description

The process of compounding sterile preparations and aseptic technique within legal and regulatory guidelines specified by USP standards.

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(4 sem hrs; 3 lec, 3 lab)

Class Type

On Campus Course

Syllabus Information


Sterile Compounding and Aseptic Technique


1 bottle of isopropyl alcohol, 1 box of latex gloves


Student Performance

(minimum competencies) After studying the material presented in this course of study, the student will be able to do the following as evaluated by the faculty in the department/program.
Upon completion of PHRA 1445, the student will be able to:
  1. Perform dose calculations in preparation of parenteral drugs
  2. Know the JCAHO requirements for pharmacy operation
  3. Recognize terminology pertaining to sterile products
  4. Understand how laminar flow hoods work
  5. Describe the major routes of parenteral administration
  6. Demonstrate proper procedure in aseptic technique
  7. Explain special precautions for injectable antineoplastic agents
  8. Define terminology pertaining to sterile products
  9. Process IV and TPN labels
  10. Demonstrate proper compounding technique
  11. Demonstrate proper aseptic technique
  12. Demonstrate knowledge of basic pharmacy technician regulations in Texas.
  13. Calculations
  14. Earn ACPE certification for sterile compounding (more information in class)


Students Rights and Responsibilities

Student Rights and Responsibilities

Log in using the AC Connect Portal

In order to receive your AC Connect Email, you must log in through AC Connect at .

If you are an active staff or faculty member according to Human Resources, use "Exchange". All other students, use "AC Connect (Google) Email".

Expected Student Behavior

Adult, professional behavior is expected at all times.
Academic dishonesty will result in a final grade of "F" for the course. Any attempt to cheat will be considered as academic dishonesty and will result in a final grade of “F” for the course.

Grading Criteria

The final course grade will be computed as follows:
Lecture grade will be 75% of overall grade
*The average of all exams equals 25% of the final grade 
*The average of ACPE exams equals 10% of the final grade
*The average of assignments and quizzes equals 10% of the final grade
*The final equals 30% of the final grade
Lab grade will be 25% of overall grade
*The average of lab practicals will equal 15% of the final grade
*Process Validation checklists equals 10% of the final grade
The following grade scale applies:
A = 95-100%
B = 85-94%
C = 75-84%
F = Less than 75%
Illegible work will not be graded.
Students will not be allowed to make-up exams, assignments, quizzes or process validations. The student will receive a grade of ZERO for anything missed.
**With regard to exams only, the instructor will consider only written petitions for emergency situations and undue hardships on an individual basis. The decision of the instructor to accept or reject the petition is final. The process must be initiated by the student and occur within 48 hours of the missed class period.

***For ACPE Credit: A passing grade of 75% or higher is required on the ACPE exams with the possibility of one retake (the average of the exams will be taken in the case of a retake) 100% adherence to the aseptic technique principals outline on the validation forms. You will be allowed only 2 chances to perform the validation with 100% adherence. If you fail any of the validations or exams, you will not receive ACPE Sterile Compounding Certification.



There will be 4 exams, 2 ACPE exams, Chapter assignments, Chapter quizzes, Process Validation Checklists, and 2 lab practicals.(This is subject to change)
A comprehensive final exam will be given on the last class meeting which will include ACPE exams.
Course outline will be given to the student at the beginning of the course. (This is subject to change.)
**Textbook homework and Process Validations will be announced in class

Lecture Schedule

Lab Schedule

Week 1

Ch 1 Sterile Compounding as a Pharmacy Technician

Safety Rules

Understanding Process Evaluations

Week 2

Ch 2 The Sterile Compounding Env

Hood and Clean Room check

Needles, Syringes, IV solutions, sharps, and tubing

Worksheet: Reading Syringes

Worksheet: IV solutions

Week 3

Ch 3 Sterile Compounding Supplies

Exam 1 Ch 1-3

Lab Ch 3

Practice Needle/Syringes

Homework: Package Inserts

Week 4

Ch.4 Medication Orders and Labeling

Lab Ch 4

Practice Inpatient/IV labels

Worksheets: Reading medication labels

Week 5

Ch. 5 Calculations

Lab Ch 5

Worksheets: Calculations

Week 6

Ch. 6 Aseptic Garbing, Hand washing, and Gloving

Exam 2 Ch 4-6

USP 797

Lab Ch 6

Lab Ch 7

Week 7

Ch. 7 Cleaning Hood


Handwash PV

Hood Clean PV

Week 8

Ch 8 Large Volumes

ACPE Med Term Ch 1-7

Lab Ch 8


Week 9

Spring Break

Spring Break

Week 10

Ch 9 Small Volume Drips

Lab Ch 9


Hep B exercise

Week 11

Ch. 10 Ampules

Exam 3 Ch 7-10

Lab Practical 1 which will be Ch 8 PV and Ch 9 PV

Lab Ch 10

Week 12

Ch 11 Narcotics

Ch 10 PV

Lab Ch 11

Week 13

Ch 12 Pediatrics

Ch 11 PV

Lab Ch 12

Week 14

Ch 13 TPN

Lab practical 2 which will include Ch 12 PV

Lab Ch 13

Lab Ch 14

Week 15

Ch 14 Chemotherapy

Exam 4 Ch 11-14


Chemo PV

Week 16

Final Exam (comprehensive)

ACPE Final Ch 8-14



Additional Information

Syllabus Created on:

01/12/22 10:11 AM

Last Edited on:

01/12/22 10:13 AM